Short update on the lithium…
Today I doubled my dose from 300 mg to 600 mg (12 mmol Li+). After two weeks at 300 mg, I can’t really say, that I have felt anything. My mood was good for the first week, and I thought, that I might be starting to feel an effect. However, these last three nights, I have sleept about 6 hours in total – one night I did not sleep at all. This is despite the fact that I took 25 mg of Seroquel before going to bed. I does not seem to have any significant effect on me, apart from making me a little bit groggy in the morning. I’ve thought about upping the dosage to 50 mg before bedtime, but given quetiapine’s half-life of 6 hours, I will probably feel a lot more groggy in the morning – who knows, maybe it’s worthwhile, assuming I get some sleep.
To summarize, no discernible effect of lithium as of yet. Hopefully, I will feel the famous “letterbox” in the coming weeks.
The letterbox refers to a description given by Richard Dreyfuss in Stephen Fry‘s decent BBC documentary The Secret Life of the Manic Depressive:
With Lithium, I remember driving down Mulholland Drive one night, when all of a sudden, I was aware, that I had letterbox. And it was an absolutely non-claustrophobic experience, that took the top and bottom off, and said “You can live here.”. And I was very happy to do so. I married with it, had children by it, reclaimed a career, if you want to put it that way.
(This quote is from memory, but it is fairly accurate, I believe.)
Stay sleepy!
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